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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | WPCT | YEAR | Open Season Leaderboard |
|---|---|---|---|---|
| 1 | Shane McClanahan# | .762 | 2023-2026 | |
| 2 | Trevor Bauer | .670 | 2012-2023 | |
| 3 | Pablo Lopez# | .667 | 2021-2026 | |
| 3 | Tarik Skubal# | .667 | 2022-2026 | |
| 5 | Corbin Burnes# | .658 | 2020-2026 | |
| 6 | Sandy Koufax | .655 | 1955-1966 | |
| 7 | David Price | .651 | 2009-2023 | |
| 8 | Matt Belisle | .647 | 2004-2018 | |
| 9 | Shohei Ohtani# | .644 | 2018-2026 | |
| 10 | Jeff Locke | .633 | 2011-2017 | |
| 11 | Justin Verlander# | .629 | 2007-2026 | |
| 12 | Josh M. Johnson | .627 | 2006-2017 | |
| 12 | Jacob Degrom# | .627 | 2012-2026 | |
| 14 | Chad Billingsley | .608 | 2007-2015 | |
| 15 | CC Sabathia | .607 | 2002-2020 | |
| 15 | Walker Buehler# | .607 | 2019-2026 | |
| 17 | Neftali Feliz | .606 | 2010-2018 | |
| 18 | Bryse Wilson# | .605 | 2020-2026 | |
| 19 | Yu Darvish# | .604 | 2012-2026 | |
| 20 | Mat Latos | .603 | 2010-2016 | |
| 21 | Jose De Leon# | .600 | 2017-2022 | |
| 22 | Lance McCullers Jr.# | .599 | 2016-2026 | |
| 23 | Nathan Eovaldi# | .597 | 2012-2026 | |
| 24 | Collin McHugh | .593 | 2010-2024 | |
| 24 | Ubaldo Jimenez | .593 | 2010-2020 | |
| 24 | Max Scherzer# | .593 | 2009-2026 | |
| 27 | Dylan Cease# | .588 | 2015-2026 | |
| 28 | Bob Feller | .587 | 1947-1956 | |
| 29 | Catfish Hunter | .586 | 1965-1976 | |
| 30 | Steve Matz# | .583 | 2010-2026 | |
| 30 | Jake Peavy | .583 | 2002-2018 | |
| 30 | Robbie Ray# | .583 | 2017-2026 | |
| 30 | Nick Pivetta# | .583 | 2019-2026 | |
| 34 | Andrew Miller | .582 | 2007-2020 | |
| 34 | Brad Ziegler | .582 | 2007-2018 | |
| 36 | Jerry Blevins | .581 | 2008-2018 | |
| 37 | Michael Lorenzen# | .578 | 2018-2026 | |
| 38 | Max Fried# | .576 | 2018-2026 | |
| 39 | Marcus Stroman# | .575 | 2015-2026 | |
| 40 | Logan Webb# | .574 | 2015-2026 | |
| 41 | Yusei Kikuchi# | .573 | 2019-2026 | |
| 42 | Clayton Kershaw# | .572 | 2009-2025 | |
| 43 | Danny Salazar | .571 | 2010-2021 | |
| 44 | Jake Odorizzi | .570 | 2012-2023 | |
| 44 | Tom Gorzelanny | .570 | 2007-2016 | |
| 46 | Shane Bieber# | .568 | 2020-2026 | |
| 47 | Matt Andriese | .566 | 2012-2023 | |
| 47 | Tyler Glasnow# | .566 | 2017-2026 | |
| 47 | Ian Kennedy | .566 | 2010-2022 | |
| 47 | Wily Peralta | .566 | 2012-2019 | |
| 51 | Zac Gallen# | .565 | 2020-2026 | |
| 51 | Lucas Giolito# | .565 | 2016-2026 | |
| 53 | Steve Hamilton | .563 | 1961-1972 | |
| 53 | Freddy Peralta# | .563 | 2019-2026 | |
| 55 | Tim Lincecum | .562 | 2009-2018 | |
| 55 | Stephen Strasburg | .562 | 2010-2025 | |
| 57 | Kyle Gibson# | .561 | 2010-2025 | |
| 57 | Jesse Chavez# | .561 | 2010-2025 | |
| 59 | Jose Berrios# | .560 | 2016-2026 | |
| 59 | Aaron Nola# | .560 | 2015-2026 | |
| 61 | Scott Baker | .559 | 2006-2014 | |
| 61 | Jose Leclerc# | .559 | 2018-2026 | |
| 63 | Santiago Casilla | .557 | 2005-2017 | |
| 64 | Oliver Perez | .556 | 2003-2022 | |
| 64 | Brandon Woodruff# | .556 | 2015-2026 | |
| 64 | Jarrod Parker | .556 | 2012-2015 | |
| 67 | Carlos Rodon# | .554 | 2015-2026 | |
| 68 | Joe Nathan | .553 | 2000-2016 | |
| 68 | Joe Musgrove# | .553 | 2012-2026 | |
| 68 | Joe Smith | .553 | 2008-2022 | |
| 71 | Gerrit Cole# | .552 | 2012-2026 | |
| 72 | Andrew Cashner | .551 | 2011-2020 | |
| 72 | Hunter Greene# | .551 | 2022-2026 | |
| 72 | Smith Smith | .551 | 2004-2017 | |
| 72 | Brad Keller# | .551 | 2017-2026 | |
| 76 | Luis Severino# | .550 | 2016-2026 | |
| 77 | Ranger Suarez# | .549 | 2020-2026 | |
| 78 | Matt Strahm# | .548 | 2016-2026 | |
| 78 | Darren O'Day | .548 | 2010-2022 | |
| 80 | Johnny Cueto | .547 | 2010-2023 | |
| 80 | Matt Cain | .547 | 2006-2019 | |
| 82 | German Marquez# | .544 | 2018-2025 | |
| 83 | Ricky Nolasco | .543 | 2007-2017 | |
| 83 | Adam Wainwright | .543 | 2004-2023 | |
| 83 | Corey Kluber | .543 | 2011-2023 | |
| 86 | Chris Sale# | .542 | 2011-2026 | |
| 86 | Felix Hernandez | .542 | 2005-2021 | |
| 86 | Jon Lester | .542 | 2007-2021 | |
| 89 | Rich Harden | .541 | 2004-2013 | |
| 89 | Matthew Boyd# | .541 | 2019-2026 | |
| 91 | Justin Masterson | .540 | 2010-2016 | |
| 92 | Larry Dierker | .539 | 1964-1976 | |
| 93 | Framber Valdez# | .538 | 2022-2026 | |
| 93 | Cole Hamels | .538 | 2007-2022 | |
| 95 | David Robertson# | .536 | 2010-2026 | |
| 95 | Zack Wheeler# | .536 | 2010-2026 | |
| 95 | George Kirby# | .536 | 2023-2026 | |
| 95 | Chris Paddack# | .536 | 2020-2026 | |
| 99 | Matt Harvey | .535 | 2014-2021 | |
| 100 | Johnny Antonelli | .534 | 1948-1961 |
