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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Saenz, Dustin | RP | Danville Raiders | 26 | 06/02/1999 | Corpus Christi | USA | Left | Left | 5' 11" | 190 lbs | - |
| Salina, Michael | 1B | Easton Grays | 22 | 01/30/2004 | Rochester | USA | Right | Right | 6' 1" | 215 lbs | - |
| Saltiban, Devin | SS | Alexandria Dukes | 21 | 02/14/2005 | Hilo | USA | Right | Right | 5' 9" | 175 lbs | - |
| Samaniego, Tyler | RP | Brunswick Pilots | 27 | 01/30/1999 | Huntsville | USA | Right | Left | 6' 4" | 205 lbs | - |
| Sanabria, Romeo | 1B | Newport News Destroyers | 23 | 05/02/2002 | Unknown | USA | Left | Right | 6' 2" | 200 lbs | - |
| Santana, Leandro | 1B | Winston-Salem Smokers | 29 | 02/19/1997 | Santo Domingo | DOM | Right | Right | 6' 2" | 185 lbs | - |
| Scherff, Alex | RP | Brunswick Pilots | 28 | 02/05/1998 | Unknown | USA | Switch | Right | 6' 3" | 210 lbs | - |
| Schultz, Thomas | RP | Brunswick Pilots | 26 | 08/03/1999 | Unknown | USA | Right | Right | 6' 6" | 215 lbs | - |
| Schwartz, JT | 1B | Danville Raiders | 26 | 12/17/1999 | Newport Beach | USA | Left | Right | 6' 4" | 215 lbs | - |
| Seig, Hayden | RP | Kingston Buccaneers | 27 | 09/10/1998 | Mechanicsburg | USA | Right | Right | 6' 5" | 225 lbs | - |
| Sepulveda, Carlos | 2B | Kingston Buccaneers | 29 | 08/27/1996 | Monclova | MEX | Left | Right | 5' 10" | 175 lbs | - |
| Serretti, Danny | SS | Prince William Panthers | 25 | 05/07/2000 | Mound City | USA | Switch | Right | 6' 0" | 185 lbs | - |
| Servideo, Anthony | SS | Winston-Salem Smokers | 26 | 03/11/1999 | Jupiter | USA | Left | Right | 5' 10" | 175 lbs | - |
| Severino, Jhonny | 3B | Newport News Destroyers | 21 | 11/08/2004 | Santo Domingo | DOM | Right | Right | 6' 3" | 185 lbs | - |
| Severino, Yunior | 2B | Wilmington Blue Rocks | 25 | 10/03/2000 | Santo Domingo | DOM | Switch | Right | 6' 1" | 185 lbs | - |
| Shaffner, Andrew | RP | Prince William Panthers | 23 | 12/31/2002 | Galax | USA | Left | Right | 6' 2" | 185 lbs | - |
| Shaver, AJ | 2B | Free Agent | 24 | 10/08/2001 | Clermont | USA | Right | Right | 6' 2" | 215 lbs | - |
| Shliger, Luke | C | Prince William Panthers | 24 | 09/25/2001 | Danbury | USA | Left | Right | 5' 9" | 170 lbs | - |
| Shojinaga, Kodey | C | Alexandria Dukes | 23 | 02/22/2003 | Honolulu | USA | Right | Right | 5' 10" | 190 lbs | - |
| Sirota, Mike | RF | Newport News Destroyers | 22 | 06/16/2003 | New York | USA | Right | Right | 6' 2" | 175 lbs | - |
| Smith, Austin | SP | Wilmington Blue Rocks | 26 | 06/22/1999 | Cedar Park | USA | Right | Right | 6' 3" | 200 lbs | - |
| Smith, Boston | LF | Prince William Panthers | 23 | 11/28/2002 | Vandalia | USA | Left | Right | 5' 10" | 195 lbs | - |
| Smith, Myles | LF | Kingston Buccaneers | 23 | 07/09/2002 | Inglewood | USA | Left | Right | 6' 1" | 205 lbs | - |
| Smith, Sincere | SS | Winston-Salem Smokers | 25 | 03/13/2000 | Elizabethtown | USA | Right | Right | 5' 11" | 170 lbs | - |
| Sommer, Tommy | SP | Alexandria Dukes | 27 | 09/25/1998 | Carmel | USA | Left | Left | 6' 4" | 220 lbs | - |
| Sosa, Thomas | CF | Easton Grays | 21 | 01/18/2005 | Mella | DOM | Left | Left | 6' 1" | 160 lbs | - |
| Spain, Dylan | RP | Free Agent | 27 | 06/21/1998 | Honolulu | USA | Right | Right | 6' 6" | 205 lbs | - |
| Stallings, Garrett | RP | Easton Grays | 28 | 08/08/1997 | Chesapeake | USA | Right | Right | 6' 2" | 200 lbs | - |
| Steward, Casey | RP | Wilmington Blue Rocks | 24 | 08/02/2001 | Wichita | USA | Right | Right | 6' 5" | 260 lbs | - |
| Strahm, Kellen | RF | Danville Raiders | 28 | 04/25/1997 | Eugene | USA | Right | Right | 6' 1" | 215 lbs | - |
| Strickland, Samuel | SP | Wilmington Blue Rocks | 26 | 03/26/1999 | Birmingham | USA | Right | Left | 6' 2" | 220 lbs | - |
| Sullivan, Sean | RP | Brunswick Pilots | 25 | 08/02/2000 | Woodland Hills | USA | Right | Right | 6' 1" | 175 lbs | - |
